In a large bowl, combine the ground chicken, egg, breadcrumbs, milk, salt, black pepper, granulated garlic, oregano, red pepper flakes, and hot sauce until well combined. Shape into 1 inch balls, you'll get around 15 meatballs.
Set up a dredging station by placing the flour in one bowl, the whisked eggs in a second bowl and the panko breadcrumbs in a third. Dredge the meatballs by rolling in flour first, then in egg and finally in panko until well coated. Set aside.
Fill a large saucepan with about 2 to 3 inches of oil. Set over moderate heat and bring up to 350°F. Once the temperature is reached, carefully lower a few meatballs at a time and fry, turning often, until golden brown and fully cooked through, about 5 minutes. Use a slotted spoon to transfer to a plate lined with paper towels to soak up the excess grease. Transfer to a wire rack set over a baking sheet and keep warm in a 250°F oven while you fry the remaining meatballs.
To make the Nashville hot sauce, carefully whisk together the spices, brown sugar, and 3/4 cup of the hot frying oil until dissolved and evenly combined. Immediately pour the sauce over the meatballs. Serve with ranch and pickles. Enjoy!